Names & Taxonomy
- Uniprot ID:
- Q9NZM6
- Entry Name:
- PK2L2_HUMAN
- Status:
- reviewed
- Protein Names:
- Polycystic kidney disease 2-like 2 protein (Polycystin-2L2) (Polycystin-L2)
- Gene Names:
- PKD2L2
- Gene Names Primary:
- PKD2L2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 624
- Sequence:
- MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDENEIQNAEQMKKWKERLEKKYYSMEIQDDYQPVTQEEFRELFLYAVELEKELHYINLKLNQVVRKVSAL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- May function as a subunit of a cation channel and play a role in fertilization.
- Gene Ontology Go:
- integral component of membrane
calcium channel activity
calcium ion binding
calcium ion transmembrane transport
detection of mechanical stimulus - Gene Ontology Biological Process:
- calcium ion transmembrane transport
detection of mechanical stimulus - Gene Ontology Molecular Function:
- calcium channel activity
calcium ion binding - Gene Ontology Cellular Component:
- integral component of membrane
- Keywords:
- Alternative splicing
Coiled coil
Complete proteome
Glycoprotein
Ion channel
Ion transport
Membrane
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport