Names & Taxonomy
- Uniprot ID:
- Q9NRM0
- Entry Name:
- GTR9_HUMAN
- Status:
- reviewed
- Protein Names:
- Solute carrier family 2, facilitated glucose transporter member 9 (Glucose transporter type 9) (GLUT-9)
- Gene Names:
- SLC2A9 GLUT9
- Gene Names Primary:
- SLC2A9
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 540
- Sequence:
- MARKQNRNSKELGLVPLTDDTSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEKIDSAVTDGKINGRP
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Isoform 1: Basolateral cell membrane
Function
- Function:
- Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate.
- Cross Reference Drug Bank:
- DB00678 DB01032
- Gene Ontology Go:
- apical plasma membrane
basolateral plasma membrane
integral component of membrane
plasma membrane
glucose transmembrane transporter activity
sugar:proton symporter activity
urate transmembrane transporter activity
glucose transport
organic acid transmembrane transport
proton transport
transmembrane transport
urate metabolic process - Gene Ontology Biological Process:
- glucose transport
organic acid transmembrane transport
proton transport
transmembrane transport
urate metabolic process - Gene Ontology Molecular Function:
- glucose transmembrane transporter activity
sugar:proton symporter activity
urate transmembrane transporter activity - Gene Ontology Cellular Component:
- apical plasma membrane
basolateral plasma membrane
integral component of membrane
plasma membrane - Keywords:
- Alternative splicing
Cell membrane
Complete proteome
Disease mutation
Glycoprotein
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Sugar transport
Transmembrane
Transmembrane helix
Transport