Names & Taxonomy
- Uniprot ID:
- Q8IVB4
- Entry Name:
- SL9A9_HUMAN
- Status:
- reviewed
- Protein Names:
- Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9)
- Gene Names:
- SLC9A9 NHE9 Nbla00118
- Gene Names Orf:
- Nbla00118
- Gene Names Primary:
- SLC9A9
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 645
- Sequence:
- MERQSRVMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLILRYATAPTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQTLGQSQLN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Late endosome membrane
Function
- Function:
- May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell.
- Gene Ontology Go:
- integral component of membrane
late endosome membrane
recycling endosome
sodium:proton antiporter activity
ion transport
regulation of pH
transmembrane transport - Gene Ontology Biological Process:
- ion transport
regulation of pH
transmembrane transport - Gene Ontology Molecular Function:
- sodium:proton antiporter activity
- Gene Ontology Cellular Component:
- integral component of membrane
late endosome membrane
recycling endosome - Keywords:
- Antiport
Autism
Autism spectrum disorder
Chromosomal rearrangement
Complete proteome
Endosome
Glycoprotein
Ion transport
Membrane
Polymorphism
Reference proteome
Sodium
Sodium transport
Transmembrane
Transmembrane helix
Transport - Interacts With:
- Q8IUH5