Names & Taxonomy
- Uniprot ID:
- P61626
- Entry Name:
- LYSC_HUMAN
- Status:
- reviewed
- Protein Names:
- Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C)
- Gene Names:
- LYZ LZM
- Gene Names Primary:
- LYZ
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 148
- Sequence:
- MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
- Catalytic Activity:
- Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
- Active Site:
- ACT_SITE 53 53; ACT_SITE 71 71
- Cross Reference Drug Bank:
- DB00128
- Gene Ontology Go:
- extracellular exosome
extracellular region
extracellular space
identical protein binding
lysozyme activity
cellular protein metabolic process
cytolysis
defense response to bacterium
inflammatory response
retina homeostasis - Gene Ontology Biological Process:
- cellular protein metabolic process
cytolysis
defense response to bacterium
inflammatory response
retina homeostasis - Gene Ontology Molecular Function:
- identical protein binding
lysozyme activity - Gene Ontology Cellular Component:
- extracellular exosome
extracellular region
extracellular space - Keywords:
- 3D-structure
Amyloid
Amyloidosis
Antimicrobial
Bacteriolytic enzyme
Complete proteome
Direct protein sequencing
Disease mutation
Disulfide bond
Glycosidase
Hydrolase
Polymorphism
Reference proteome
Secreted
Signal - Interacts With:
- Itself