Names & Taxonomy
- Uniprot ID:
- P12109
- Entry Name:
- CO6A1_HUMAN
- Status:
- reviewed
- Protein Names:
- Collagen alpha-1(VI) chain
- Gene Names:
- COL6A1
- Gene Names Primary:
- COL6A1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1028
- Sequence:
- MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQTVSRKVALG
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix
Function
- Function:
- Collagen VI acts as a cell-binding protein.
- Gene Ontology Go:
- collagen type VI trimer
endoplasmic reticulum lumen
extracellular exosome
extracellular matrix
extracellular region
lysosomal membrane
membrane
protein complex
sarcolemma
platelet-derived growth factor binding
axon guidance
cell adhesion
cellular response to amino acid stimulus
collagen catabolic process
endodermal cell differentiation
extracellular matrix disassembly
extracellular matrix organization
osteoblast differentiation
protein heterotrimerization - Gene Ontology Biological Process:
- axon guidance
cell adhesion
cellular response to amino acid stimulus
collagen catabolic process
endodermal cell differentiation
extracellular matrix disassembly
extracellular matrix organization
osteoblast differentiation
protein heterotrimerization - Gene Ontology Molecular Function:
- platelet-derived growth factor binding
- Gene Ontology Cellular Component:
- collagen type VI trimer
endoplasmic reticulum lumen
extracellular exosome
extracellular matrix
extracellular region
lysosomal membrane
membrane
protein complex
sarcolemma - Keywords:
- Cell adhesion
Collagen
Complete proteome
Direct protein sequencing
Disease mutation
Extracellular matrix
Glycoprotein
Hydroxylation
Polymorphism
Reference proteome
Repeat
Secreted
Signal