Names & Taxonomy

Uniprot ID:
P04001
Entry Name:
OPSG_HUMAN
Status:
reviewed
Protein Names:
Medium-wave-sensitive opsin 1 (Green cone photoreceptor pigment) (Green-sensitive opsin) (GOP)
Gene Names:
OPN1MW GCP
Gene Names Primary:
OPN1MW
Organism:
Homo sapiens (Human)

Structure

Length:
364
Sequence:
MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.
Gene Ontology Go:
integral component of plasma membrane
photoreceptor outer segment membrane
plasma membrane
G-protein coupled receptor activity
photoreceptor activity
G-protein coupled receptor signaling pathway
phototransduction, visible light
positive regulation of cytokinesis
protein-chromophore linkage
retinoid metabolic process
visual perception
Gene Ontology Biological Process:
G-protein coupled receptor signaling pathway
phototransduction, visible light
positive regulation of cytokinesis
protein-chromophore linkage
retinoid metabolic process
visual perception
Gene Ontology Molecular Function:
G-protein coupled receptor activity
photoreceptor activity
Gene Ontology Cellular Component:
integral component of plasma membrane
photoreceptor outer segment membrane
plasma membrane
Keywords:
3D-structure
Cell membrane
Chromophore
Complete proteome
Disease mutation
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Phosphoprotein
Photoreceptor protein
Receptor
Reference proteome
Retinal protein
Sensory transduction
Transducer
Transmembrane
Transmembrane helix
Vision

Publication

PubMed ID:
2937147 15772651 3303660 1302020 8666378 12051694 20579627