Names & Taxonomy
- Uniprot ID:
- P00167
- Entry Name:
- CYB5_HUMAN
- Status:
- reviewed
- Protein Names:
- Cytochrome b5 (Microsomal cytochrome b5 type A) (MCB5)
- Gene Names:
- CYB5A CYB5
- Gene Names Primary:
- CYB5A
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 134
- Sequence:
- MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.; Isoform 2: Cytoplasm.
Function
- Function:
- Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
- Gene Ontology Go:
- cytoplasm
endoplasmic reticulum membrane
extracellular exosome
integral component of membrane
intracellular membrane-bounded organelle
membrane
mitochondrial outer membrane
aldo-keto reductase (NADP) activity
cytochrome-c oxidase activity
enzyme binding
heme binding
metal ion binding
hydrogen ion transmembrane transport
L-ascorbic acid metabolic process
response to cadmium ion
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Biological Process:
- hydrogen ion transmembrane transport
L-ascorbic acid metabolic process
response to cadmium ion
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Molecular Function:
- aldo-keto reductase (NADP) activity
cytochrome-c oxidase activity
enzyme binding
heme binding
metal ion binding - Gene Ontology Cellular Component:
- cytoplasm
endoplasmic reticulum membrane
extracellular exosome
integral component of membrane
intracellular membrane-bounded organelle
membrane
mitochondrial outer membrane - Keywords:
- 3D-structure
Acetylation
Alternative splicing
Complete proteome
Cytoplasm
Direct protein sequencing
Electron transport
Endoplasmic reticulum
Heme
Iron
Membrane
Metal-binding
Microsome
Reference proteome
Transmembrane
Transmembrane helix
Transport