Names & Taxonomy

Uniprot ID:
G3CA49
Entry Name:
G3CA49_HUMAN
Status:
unreviewed
Protein Names:
Cytochrome c oxidase subunit 2 (Fragment)
Gene Names:
COX2
Gene Names Primary:
COX2
Organism:
Homo sapiens (Human)

Structure

Length:
225
Sequence:
HAAQVGLQDATSPIMEELITFHDHALMIIFLICFLVLYALFLTLTTKLTNTNISDAQEMETVWTILPAIILVLIALPSLRILYMTDEVNDPSLTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLEPGDLRLLDVDNRVVLPIEAPIRMMITSQDVLHSWAVPTLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKIFEMGXVFTL

Subcellular location

Subcellular Location:
Mitochondrion inner membrane
Gene Encoded:
Mitochondrion

Function

Function:
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
Cofactor:
COFACTOR: Name=Cu cation; Xref=ChEBI:CHEBI:23378;
Gene Ontology Go:
integral component of membrane
mitochondrial inner membrane
respiratory chain
copper ion binding
cytochrome-c oxidase activity
electron transport chain
Gene Ontology Biological Process:
electron transport chain
Gene Ontology Molecular Function:
copper ion binding
cytochrome-c oxidase activity
Gene Ontology Cellular Component:
integral component of membrane
mitochondrial inner membrane
respiratory chain
Keywords:
Copper
Electron transport
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Respiratory chain
Transmembrane
Transmembrane helix
Transport