Names & Taxonomy

Uniprot ID:
E7ES21
Entry Name:
E7ES21_HUMAN
Status:
unreviewed
Protein Names:
Hephaestin
Gene Names:
HEPH
Gene Names Primary:
HEPH
Organism:
Homo sapiens (Human)

Structure

Length:
969
Sequence:
MWAMESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ
Proteomes:
UP000005640

Function

Gene Ontology Go:
integral component of membrane
plasma membrane
copper ion binding
oxidoreductase activity
cellular iron ion homeostasis
iron ion transport
Gene Ontology Biological Process:
cellular iron ion homeostasis
iron ion transport
Gene Ontology Molecular Function:
copper ion binding
oxidoreductase activity
Gene Ontology Cellular Component:
integral component of membrane
plasma membrane
Keywords:
Complete proteome
Copper
Membrane
Metal-binding
Oxidoreductase
Proteomics identification
Reference proteome
Signal
Transmembrane
Transmembrane helix

Publication

PubMed ID:
15772651