Names & Taxonomy
- Uniprot ID:
- C9JR72
- Entry Name:
- KBTBD_HUMAN
- Status:
- reviewed
- Protein Names:
- Kelch repeat and BTB domain-containing protein 13
- Gene Names:
- KBTBD13
- Gene Names Primary:
- KBTBD13
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 458
- Sequence:
- MARGPQTLVQVWVGGQLFQADRALLVEHCGFFRGLFRSGMRETRAAEVRLGVLSAGGFRATLQVLRGDRPALAAEDELLQAVECAAFLQAPALARFLEHNLTSDNCALLCDAAAAFGLRDVFHSAALFICDGERELAAELALPEARAYVAALRPSSYAAVSTHTPAPGFLEDASRTLCYLDEEEDAWRTLAALPLEASTLLAGVATLGNKLYIVGGVRGASKEVVELGFCYDPDGGTWHEFPSPHQPRYDTALAGFDGRLYAIGGEFQRTPISSVERYDPAAGCWSFVADLPQPAAGVPCAQACGRLFVCLWRPADTTAVVEYAVRTDAWLPVAELRRPQSYGHCMVAHRDSLYVVRNGPSDDFLHCAIDCLNLATGQWTALPGQFVNSKGALFTAVVRGDTVYTVNRMFTLLYAIEGGTWRLLREKAGFPRPGSLQTFLLRLPPGAPGPVTSTTAEL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.
- Pathway:
- Protein modification; protein ubiquitination.
- Gene Ontology Go:
- Cul3-RING ubiquitin ligase complex
cytoplasm
protein ubiquitination - Gene Ontology Biological Process:
- protein ubiquitination
- Gene Ontology Cellular Component:
- Cul3-RING ubiquitin ligase complex
cytoplasm - Keywords:
- Complete proteome
Cytoplasm
Disease mutation
Kelch repeat
Nemaline myopathy
Reference proteome
Repeat
Ubl conjugation
Ubl conjugation pathway