Names & Taxonomy

Uniprot ID:
B7Z2A9
Entry Name:
B7Z2A9_HUMAN
Status:
unreviewed
Protein Names:
V-type proton ATPase subunit a
Gene Names:
ATP6V0A1
Gene Names Primary:
ATP6V0A1
Organism:
Homo sapiens (Human)

Structure

Length:
794
Sequence:
MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEMADPDLLEESSSLLEPSEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLNIFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
Proteomes:
UP000005640

Function

Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Gene Ontology Go:
integral component of membrane
vacuolar proton-transporting V-type ATPase, V0 domain
hydrogen ion transmembrane transporter activity
ATP hydrolysis coupled proton transport
Gene Ontology Biological Process:
ATP hydrolysis coupled proton transport
Gene Ontology Molecular Function:
hydrogen ion transmembrane transporter activity
Gene Ontology Cellular Component:
integral component of membrane
vacuolar proton-transporting V-type ATPase, V0 domain
Keywords:
Complete proteome
Hydrogen ion transport
Ion transport
Membrane
Proteomics identification
Reference proteome
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
16625196 24275569