Names & Taxonomy
- Uniprot ID:
- A0A024R906
- Entry Name:
- A0A024R906_HUMAN
- Status:
- unreviewed
- Protein Names:
- Discoidin domain receptor family, member 2, isoform CRA_a
- Gene Names:
- DDR2 hCG_14697
- Gene Names Orf:
- hCG_14697
- Gene Names Primary:
- DDR2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 855
- Sequence:
- MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE
Function
- Gene Ontology Go:
- integral component of plasma membrane
ATP binding
protein tyrosine kinase collagen receptor activity
biomineral tissue development
chondrocyte proliferation
collagen fibril organization
endochondral bone growth
positive regulation of extracellular matrix disassembly
positive regulation of fibroblast migration
positive regulation of fibroblast proliferation - Gene Ontology Biological Process:
- biomineral tissue development
chondrocyte proliferation
collagen fibril organization
endochondral bone growth
positive regulation of extracellular matrix disassembly
positive regulation of fibroblast migration
positive regulation of fibroblast proliferation - Gene Ontology Molecular Function:
- ATP binding
protein tyrosine kinase collagen receptor activity - Gene Ontology Cellular Component:
- integral component of plasma membrane
- Keywords:
- Membrane
Receptor
Signal
Transmembrane
Transmembrane helix
Publication
- PubMed ID:
- 11181995