Names & Taxonomy
- Uniprot ID:
- B4DFL1
- Entry Name:
- B4DFL1_HUMAN
- Status:
- unreviewed
- Protein Names:
- Dihydrolipoyl dehydrogenase (EC 1.8.1.4)
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 459
- Sequence:
- MLMYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF
Function
- Catalytic Activity:
- Protein N(6)-(dihydrolipoyl)lysine + NAD(+) = protein N(6)-(lipoyl)lysine + NADH.
- Cofactor:
- COFACTOR: Name=FAD; Xref=ChEBI:CHEBI:57692;
- Gene Ontology Go:
- cell
dihydrolipoyl dehydrogenase activity
flavin adenine dinucleotide binding
cell redox homeostasis - Gene Ontology Biological Process:
- cell redox homeostasis
- Gene Ontology Molecular Function:
- dihydrolipoyl dehydrogenase activity
flavin adenine dinucleotide binding - Gene Ontology Cellular Component:
- cell
- Keywords:
- FAD
Flavoprotein
NAD
Oxidoreductase
Redox-active center