Names & Taxonomy

Uniprot ID:
A0A024R791
Entry Name:
A0A024R791_HUMAN
Status:
unreviewed
Protein Names:
V-type proton ATPase subunit a
Gene Names:
ATP6V0A4 hCG_16392
Gene Names Orf:
hCG_16392
Gene Names Primary:
ATP6V0A4
Organism:
Homo sapiens (Human)

Structure

Length:
840
Sequence:
MVSVFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNMNVNSFQRKFVNEVRRCESLERILRFLEDEMQNEIVVQLLEKSPLTPLPREMITLETVLEKLEGELQEANQNQQALKQSFLELTELKYLLKKTQDFFETETNLADDFFTEDTSGLLELKAVPAYMTGKLGFIAGVINRERMASFERLLWRICRGNVYLKFSEMDAPLEDPVTKEEIQKNIFIIFYQGEQLRQKIKKICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHRQRLLQEAAANWHSWLIKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQGMELSGSSMAPIMTTVQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGTVMLLAALWMILNERRLLSQKTDNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVQPMFRNGTWNTHVMEESLYLQLDPAIPGVYFGNPYPFGIDPIWNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMIFILCLFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQSFFVVMALISVPWMLLIKPFILRASHRKSQLQASRIQEDATENIEGDSSSPSSRSGQRTSADTHGALDDHGEEFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVMNSGLQTRGWGGIVGVFIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYVGDGYKFSPFSFKHILDGTAEE

Function

Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Gene Ontology Go:
apical plasma membrane
brush border
endosome
integral component of membrane
vacuolar proton-transporting V-type ATPase, V0 domain
hydrogen ion transmembrane transporter activity
ATP hydrolysis coupled proton transport
Gene Ontology Biological Process:
ATP hydrolysis coupled proton transport
Gene Ontology Molecular Function:
hydrogen ion transmembrane transporter activity
Gene Ontology Cellular Component:
apical plasma membrane
brush border
endosome
integral component of membrane
vacuolar proton-transporting V-type ATPase, V0 domain
Keywords:
Coiled coil
Hydrogen ion transport
Ion transport
Membrane
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
11181995