Names & Taxonomy

Uniprot ID:
B2RBW5
Entry Name:
B2RBW5_HUMAN
Status:
unreviewed
Protein Names:
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.-)
Organism:
Homo sapiens (Human)

Structure

Length:
780
Sequence:
MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMVMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ

Subcellular location

Subcellular Location:
Mitochondrion

Function

Cofactor:
COFACTOR: Name= cluster; Xref=ChEBI:CHEBI:49883;
Gene Ontology Go:
mitochondrion
4 iron, 4 sulfur cluster binding
aconitate hydratase activity
metal ion binding
tricarboxylic acid cycle
Gene Ontology Biological Process:
tricarboxylic acid cycle
Gene Ontology Molecular Function:
4 iron, 4 sulfur cluster binding
aconitate hydratase activity
metal ion binding
Gene Ontology Cellular Component:
mitochondrion
Keywords:
Iron
Iron-sulfur
Lyase
Metal-binding
Mitochondrion
Transit peptide