Names & Taxonomy
- Uniprot ID:
- B0ZBD3
- Entry Name:
- B0ZBD3_HUMAN
- Status:
- unreviewed
- Protein Names:
- Adrenergic, alpha-1A-, receptor variant 3
- Gene Names:
- ADRA1A
- Gene Names Primary:
- ADRA1A
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 475
- Sequence:
- MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCTTARTKSRSVTRLECSGMILAHCNLRLPGSRDSPASASQAAGTTGMCHQADATRPS
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Gene Ontology Go:
- cytosol
integral component of membrane
T-tubule
Z disc
alpha1-adrenergic receptor activity
activation of phospholipase C activity
adult heart development
aging
calcium ion transport into cytosol
cell growth
micturition
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
negative regulation of Rho protein signal transduction
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
organ growth
phospholipase C-activating G-protein coupled receptor signaling pathway
pilomotor reflex
positive regulation of action potential
positive regulation of cardiac muscle contraction
positive regulation of ERK1 and ERK2 cascade
positive regulation of heart rate by epinephrine-norepinephrine
positive regulation of protein kinase C signaling
positive regulation of smooth muscle contraction
positive regulation of synaptic transmission, GABAergic
positive regulation of systemic arterial blood pressure
positive regulation of the force of heart contraction by epinephrine-norepinephrine
positive regulation of vasoconstriction
response to drug
response to hormone - Gene Ontology Biological Process:
- activation of phospholipase C activity
adult heart development
aging
calcium ion transport into cytosol
cell growth
micturition
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
negative regulation of Rho protein signal transduction
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
organ growth
phospholipase C-activating G-protein coupled receptor signaling pathway
pilomotor reflex
positive regulation of action potential
positive regulation of cardiac muscle contraction
positive regulation of ERK1 and ERK2 cascade
positive regulation of heart rate by epinephrine-norepinephrine
positive regulation of protein kinase C signaling
positive regulation of smooth muscle contraction
positive regulation of synaptic transmission, GABAergic
positive regulation of systemic arterial blood pressure
positive regulation of the force of heart contraction by epinephrine-norepinephrine
positive regulation of vasoconstriction
response to drug
response to hormone - Gene Ontology Molecular Function:
- alpha1-adrenergic receptor activity
- Gene Ontology Cellular Component:
- cytosol
integral component of membrane
T-tubule
Z disc - Keywords:
- Cell membrane
G-protein coupled receptor
Membrane
Receptor
Transducer
Transmembrane
Transmembrane helix