Names & Taxonomy
- Uniprot ID:
- Q9UMX9
- Entry Name:
- S45A2_HUMAN
- Status:
- reviewed
- Protein Names:
- Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Solute carrier family 45 member 2)
- Gene Names:
- SLC45A2 AIM1 MATP
- Gene Names Primary:
- SLC45A2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 530
- Sequence:
- MGSNSGQAGRHIYKSLADDGPFDSVEPPKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPVVGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMIGVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYLLGAIDWAHLELGRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPLTEVAKGIPPQQTPQDPPLSSDGMYEYGSIEKVKNGYVNPELAMQGAKNKNHAEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYERGVEVGCWGLCINSVFSSLYSYFQKVLVSYIGLKGLYFTGYLLFGLGTGFIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEEKERQQAPGGDPDNSVRGKGMDCATLTCMVQLAQILVGGGLGFLVNTAGTVVVVVITASAVALIGCCFVALFVRYVD
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Melanosome membrane
Function
- Function:
- Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By similarity).
- Gene Ontology Go:
- integral component of membrane
melanosome membrane
sucrose:proton symporter activity
developmental pigmentation
melanin biosynthetic process
response to stimulus
sucrose transport
visual perception - Gene Ontology Biological Process:
- developmental pigmentation
melanin biosynthetic process
response to stimulus
sucrose transport
visual perception - Gene Ontology Molecular Function:
- sucrose:proton symporter activity
- Gene Ontology Cellular Component:
- integral component of membrane
melanosome membrane - Keywords:
- Albinism
Alternative splicing
Complete proteome
Disease mutation
Glycoprotein
Melanin biosynthesis
Membrane
Polymorphism
Reference proteome
Sensory transduction
Transmembrane
Transmembrane helix
Vision