Names & Taxonomy
- Uniprot ID:
- Q96F07
- Entry Name:
- CYFP2_HUMAN
- Status:
- reviewed
- Protein Names:
- Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
- Gene Names:
- CYFIP2 KIAA1168 PIR121
- Gene Names Primary:
- CYFIP2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1278
- Sequence:
- MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQACQWSPRALFHPTGGTQGRRGCRSLLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA.
- Gene Ontology Go:
- cell junction
cytoplasm
cytosol
extracellular exosome
membrane
neuron projection
nucleus
perinuclear region of cytoplasm
synapse
activation of cysteine-type endopeptidase activity
apoptotic process
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
positive regulation of proteolysis
single organismal cell-cell adhesion
small GTPase mediated signal transduction
vascular endothelial growth factor receptor signaling pathway - Gene Ontology Biological Process:
- activation of cysteine-type endopeptidase activity
apoptotic process
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
positive regulation of proteolysis
single organismal cell-cell adhesion
small GTPase mediated signal transduction
vascular endothelial growth factor receptor signaling pathway - Gene Ontology Cellular Component:
- cell junction
cytoplasm
cytosol
extracellular exosome
membrane
neuron projection
nucleus
perinuclear region of cytoplasm
synapse - Keywords:
- Acetylation
Alternative splicing
Apoptosis
Cell adhesion
Cell junction
Complete proteome
Cytoplasm
Nucleus
RNA editing
Reference proteome
Synapse
Synaptosome - Interacts With:
- Q06787