Names & Taxonomy
- Uniprot ID:
- Q8TBB6
- Entry Name:
- S7A14_HUMAN
- Status:
- reviewed
- Protein Names:
- Probable cationic amino acid transporter (Solute carrier family 7 member 14)
- Gene Names:
- SLC7A14 KIAA1613
- Gene Names Primary:
- SLC7A14
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 771
- Sequence:
- MSGFFTSLDPRRVQWGAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGDNEMLIGKSDKSTYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMDRPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQEDWGGPTEDKGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Lysosome membrane
Function
- Function:
- May be involved in arginine transport.
- Gene Ontology Go:
- integral component of membrane
lysosomal membrane
antiporter activity
L-amino acid transmembrane transporter activity
L-alpha-amino acid transmembrane transport
L-amino acid transport
negative regulation of phosphatase activity - Gene Ontology Biological Process:
- L-alpha-amino acid transmembrane transport
L-amino acid transport
negative regulation of phosphatase activity - Gene Ontology Molecular Function:
- antiporter activity
L-amino acid transmembrane transporter activity - Gene Ontology Cellular Component:
- integral component of membrane
lysosomal membrane - Keywords:
- Amino-acid transport
Complete proteome
Glycoprotein
Lysosome
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Retinitis pigmentosa
Transmembrane
Transmembrane helix
Transport