Names & Taxonomy
- Uniprot ID:
- A0A0A6YY96
- Entry Name:
- A0A0A6YY96_HUMAN
- Status:
- unreviewed
- Protein Names:
- Iron-responsive element-binding protein 2
- Gene Names:
- IREB2
- Gene Names Primary:
- IREB2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 963
- Sequence:
- MDAPKAGYAFEYLIETLNDSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQKDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSICVGNTAPLSDAVLNAVKQGDLVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIYLHDIWPSREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS
- Proteomes:
- UP000005640
Function
- Gene Ontology Go:
- cytosol
mitochondrion
iron-responsive element binding
translation repressor activity
aging
cellular iron ion homeostasis
cellular response to hypoxia
erythrocyte homeostasis
intestinal absorption
iron ion transport
osteoclast differentiation
post-embryonic development
protoporphyrinogen IX biosynthetic process
response to iron(II) ion
response to retinoic acid - Gene Ontology Biological Process:
- aging
cellular iron ion homeostasis
cellular response to hypoxia
erythrocyte homeostasis
intestinal absorption
iron ion transport
osteoclast differentiation
post-embryonic development
protoporphyrinogen IX biosynthetic process
response to iron(II) ion
response to retinoic acid - Gene Ontology Molecular Function:
- iron-responsive element binding
translation repressor activity - Gene Ontology Cellular Component:
- cytosol
mitochondrion - Keywords:
- Complete proteome
Proteomics identification
Reference proteome