Names & Taxonomy
- Uniprot ID:
- Q53HM1
- Entry Name:
- Q53HM1_HUMAN
- Status:
- unreviewed
- Protein Names:
- Uridine-cytidine kinase (EC 2.7.1.48) (Uridine kinase) (Fragment)
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 548
- Sequence:
- MAAPPARADADPSPTSPPTARDTPGRQAEKSETACEDRSNAESLDRLLPPVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFDHPDAFDFDLIIFTLKKLKQGKSVKVPIYDFTTHSRKKDWKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPSFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEERELSVRAALASAHQCHPLPRTLSVLKSTPQVRGMHTIIRDKETSRDEFIFYSKRLMRLLIEHALSFLPFQDCVVQTPQGQDYAGKCYAGKQITGVSILRAGETMEPALRAVCKDVRIGTILIQTNQLTGEPELHYLRLPKDISDDHVILMDCTVSTGAAAMMAVRVLLDHDVPEDKIFLLSLLMAEMGVHSVAYAFPRVRIITTAVDKRVNDLFRIIPGIGNFGDRYFGTDAVPDGSDEEEVAYTG
Function
- Pathway:
- Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.
- Catalytic Activity:
- ATP + cytidine = ADP + CMP.
- Gene Ontology Go:
- ATP binding
uridine kinase activity
CTP salvage
UMP salvage - Gene Ontology Biological Process:
- CTP salvage
UMP salvage - Gene Ontology Molecular Function:
- ATP binding
uridine kinase activity - Keywords:
- ATP-binding
Kinase
Nucleotide-binding
Transferase