Names & Taxonomy
- Uniprot ID:
- Q14576
- Entry Name:
- ELAV3_HUMAN
- Status:
- reviewed
- Protein Names:
- ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21)
- Gene Names:
- ELAVL3 HUC PLE21
- Gene Names Primary:
- ELAVL3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 367
- Sequence:
- MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA
- Proteomes:
- UP000005640
Function
- Function:
- Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance.
- Gene Ontology Go:
- AU-rich element binding
nucleotide binding
cell differentiation
nervous system development - Gene Ontology Biological Process:
- cell differentiation
nervous system development - Gene Ontology Molecular Function:
- AU-rich element binding
nucleotide binding - Keywords:
- Alternative splicing
Complete proteome
Developmental protein
Differentiation
Neurogenesis
Phosphoprotein
RNA-binding
Reference proteome
Repeat