Names & Taxonomy
- Uniprot ID:
- Q14330
- Entry Name:
- GPR18_HUMAN
- Status:
- reviewed
- Protein Names:
- N-arachidonyl glycine receptor (NAGly receptor) (G-protein coupled receptor 18)
- Gene Names:
- GPR18 GPCRW
- Gene Names Primary:
- GPR18
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 331
- Sequence:
- MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSNINSEML
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
Function
- Function:
- Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.
- Cross Reference Drug Bank:
- DB00145
- Gene Ontology Go:
- integral component of membrane
plasma membrane
G-protein coupled receptor activity
G-protein coupled receptor signaling pathway - Gene Ontology Biological Process:
- G-protein coupled receptor signaling pathway
- Gene Ontology Molecular Function:
- G-protein coupled receptor activity
- Gene Ontology Cellular Component:
- integral component of membrane
plasma membrane - Keywords:
- Cell membrane
Complete proteome
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Phosphoprotein
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix