Names & Taxonomy
- Uniprot ID:
- Q03692
- Entry Name:
- COAA1_HUMAN
- Status:
- reviewed
- Protein Names:
- Collagen alpha-1(X) chain
- Gene Names:
- COL10A1
- Gene Names Primary:
- COL10A1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 680
- Sequence:
- MLPQIPFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix
Function
- Function:
- Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
- Gene Ontology Go:
- cell cortex
collagen trimer
endoplasmic reticulum lumen
extracellular region
proteinaceous extracellular matrix
metal ion binding
cartilage development
collagen catabolic process
endochondral ossification
extracellular matrix disassembly
extracellular matrix organization
skeletal system development - Gene Ontology Biological Process:
- cartilage development
collagen catabolic process
endochondral ossification
extracellular matrix disassembly
extracellular matrix organization
skeletal system development - Gene Ontology Molecular Function:
- metal ion binding
- Gene Ontology Cellular Component:
- cell cortex
collagen trimer
endoplasmic reticulum lumen
extracellular region
proteinaceous extracellular matrix - Keywords:
- 3D-structure
Calcium
Collagen
Complete proteome
Disease mutation
Extracellular matrix
Hydroxylation
Metal-binding
Polymorphism
Reference proteome
Repeat
Secreted
Signal - Interacts With:
- Q8N9N5; Q9UMX0; Q9UMX0-2