Names & Taxonomy
- Uniprot ID:
- Q03403
- Entry Name:
- TFF2_HUMAN
- Status:
- reviewed
- Protein Names:
- Trefoil factor 2 (Spasmolysin) (Spasmolytic polypeptide) (SP)
- Gene Names:
- TFF2 SML1
- Gene Names Primary:
- TFF2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 129
- Sequence:
- MGRRDAQLLAALLVLGLCALAGSEKPSPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWCFHPLPKQESDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWCFFPKSVEDCHY
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).
- Gene Ontology Go:
- extracellular exosome
digestion - Gene Ontology Biological Process:
- digestion
- Gene Ontology Cellular Component:
- extracellular exosome
- Keywords:
- Complete proteome
Disulfide bond
Polymorphism
Reference proteome
Repeat
Secreted
Signal - Interacts With:
- Q96PJ5