Names & Taxonomy
- Uniprot ID:
- P47929
- Entry Name:
- LEG7_HUMAN
- Status:
- reviewed
- Protein Names:
- Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced gene 1 protein)
- Gene Names:
- LGALS7 PIG1; LGALS7B
- Gene Names Orf:
- ;
- Gene Names Primary:
- LGALS7; LGALS7B
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 136
- Sequence:
- MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
- Gene Ontology Go:
- cytoplasm
extracellular exosome
extracellular space
nucleus
carbohydrate binding
apoptotic process
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules - Gene Ontology Biological Process:
- apoptotic process
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules - Gene Ontology Molecular Function:
- carbohydrate binding
- Gene Ontology Cellular Component:
- cytoplasm
extracellular exosome
extracellular space
nucleus - Keywords:
- 3D-structure
Apoptosis
Complete proteome
Cytoplasm
Direct protein sequencing
Lectin
Nucleus
Reference proteome
Secreted