Names & Taxonomy
- Uniprot ID:
- P47872
- Entry Name:
- SCTR_HUMAN
- Status:
- reviewed
- Protein Names:
- Secretin receptor (SCT-R)
- Gene Names:
- SCTR
- Gene Names Primary:
- SCTR
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 440
- Sequence:
- MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
Function
- Function:
- This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
- Cross Reference Drug Bank:
- DB00021
- Gene Ontology Go:
- cytoplasmic microtubule
integral component of plasma membrane
plasma membrane
secretin receptor activity
cell surface receptor signaling pathway
digestion
excretion
G-protein coupled receptor signaling pathway - Gene Ontology Biological Process:
- cell surface receptor signaling pathway
digestion
excretion
G-protein coupled receptor signaling pathway - Gene Ontology Molecular Function:
- secretin receptor activity
- Gene Ontology Cellular Component:
- cytoplasmic microtubule
integral component of plasma membrane
plasma membrane - Keywords:
- Cell membrane
Complete proteome
G-protein coupled receptor
Glycoprotein
Membrane
Polymorphism
Receptor
Reference proteome
Signal
Transducer
Transmembrane
Transmembrane helix