Names & Taxonomy

Uniprot ID:
P31930
Entry Name:
QCR1_HUMAN
Status:
reviewed
Protein Names:
Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III subunit 1) (Core protein I) (Ubiquinol-cytochrome-c reductase complex core protein 1)
Gene Names:
UQCRC1
Gene Names Primary:
UQCRC1
Organism:
Homo sapiens (Human)

Structure

Length:
480
Sequence:
MAASVVCRAATAGAQVLLRARRSPALLRTPALRSTATFAQALQFVPETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSEIRHRDDALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLSSPLASGAVANKLCQSFQTFSICYAETGLLGAHFVCDRMKIDDMMFVLQGQWMRLCTSATESEVARGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDASVVREICSKYIYDQCPAVAGYGPIEQLPDYNRIRSGMFWLRF
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion inner membrane.

Function

Function:
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
Gene Ontology Go:
mitochondrial inner membrane
mitochondrial respiratory chain
mitochondrial respiratory chain complex III
mitochondrion
myelin sheath
metalloendopeptidase activity
ubiquinol-cytochrome-c reductase activity
ubiquitin protein ligase binding
zinc ion binding
aerobic respiration
cellular metabolic process
hydrogen ion transmembrane transport
mitochondrial electron transport, ubiquinol to cytochrome c
oxidation-reduction process
oxidative phosphorylation
protein processing
respiratory electron transport chain
response to activity
response to alkaloid
small molecule metabolic process
Gene Ontology Biological Process:
aerobic respiration
cellular metabolic process
hydrogen ion transmembrane transport
mitochondrial electron transport, ubiquinol to cytochrome c
oxidation-reduction process
oxidative phosphorylation
protein processing
respiratory electron transport chain
response to activity
response to alkaloid
small molecule metabolic process
Gene Ontology Molecular Function:
metalloendopeptidase activity
ubiquinol-cytochrome-c reductase activity
ubiquitin protein ligase binding
zinc ion binding
Gene Ontology Cellular Component:
mitochondrial inner membrane
mitochondrial respiratory chain
mitochondrial respiratory chain complex III
mitochondrion
myelin sheath
Keywords:
Acetylation
Complete proteome
Direct protein sequencing
Electron transport
Membrane
Mitochondrion
Mitochondrion inner membrane
Phosphoprotein
Polymorphism
Reference proteome
Respiratory chain
Transit peptide
Transport

Publication

PubMed ID:
8407948 8069229 14702039 15489334 8313870 15242332 19608861 21269460 24275569 25944712 10453733