Names & Taxonomy
- Uniprot ID:
- P31641
- Entry Name:
- SC6A6_HUMAN
- Status:
- reviewed
- Protein Names:
- Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)
- Gene Names:
- SLC6A6
- Gene Names Primary:
- SLC6A6
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 620
- Sequence:
- MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
Function
- Function:
- Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
- Gene Ontology Go:
- integral component of membrane
integral component of plasma membrane
plasma membrane
neurotransmitter:sodium symporter activity
taurine:sodium symporter activity
amino acid transmembrane transport
amino acid transport
cellular amino acid metabolic process
ion transport
taurine transport
transmembrane transport
transport - Gene Ontology Biological Process:
- amino acid transmembrane transport
amino acid transport
cellular amino acid metabolic process
ion transport
taurine transport
transmembrane transport
transport - Gene Ontology Molecular Function:
- neurotransmitter:sodium symporter activity
taurine:sodium symporter activity - Gene Ontology Cellular Component:
- integral component of membrane
integral component of plasma membrane
plasma membrane - Keywords:
- Alternative splicing
Cell membrane
Complete proteome
Glycoprotein
Membrane
Neurotransmitter transport
Phosphoprotein
Polymorphism
Reference proteome
Symport
Transmembrane
Transmembrane helix
Transport