Names & Taxonomy
- Uniprot ID:
- P27816
- Entry Name:
- MAP4_HUMAN
- Status:
- reviewed
- Protein Names:
- Microtubule-associated protein 4 (MAP-4)
- Gene Names:
- MAP4
- Gene Names Primary:
- MAP4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1152
- Sequence:
- MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNSESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm, cytoskeleton.
Function
- Function:
- Non-neuronal microtubule-associated protein. Promotes microtubule assembly.
- Cross Reference Drug Bank:
- DB01248 DB01229
- Gene Ontology Go:
- axoneme
cytoplasm
extracellular exosome
microtubule
microtubule associated complex
microtubule cytoskeleton
mitotic spindle
neuron projection
neuronal postsynaptic density
plasma membrane
microtubule binding
poly(A) RNA binding
structural molecule activity
cell division
establishment of spindle orientation
microtubule sliding
mitotic spindle organization
negative regulation of nonmotile primary cilium assembly
neuron projection development - Gene Ontology Biological Process:
- cell division
establishment of spindle orientation
microtubule sliding
mitotic spindle organization
negative regulation of nonmotile primary cilium assembly
neuron projection development - Gene Ontology Molecular Function:
- microtubule binding
poly(A) RNA binding
structural molecule activity - Gene Ontology Cellular Component:
- axoneme
cytoplasm
extracellular exosome
microtubule
microtubule associated complex
microtubule cytoskeleton
mitotic spindle
neuronal postsynaptic density
neuron projection
plasma membrane - Keywords:
- Acetylation
Alternative splicing
Complete proteome
Cytoplasm
Cytoskeleton
Direct protein sequencing
Microtubule
Phosphoprotein
Polymorphism
Reference proteome
Repeat - Interacts With:
- P16333