Names & Taxonomy
- Uniprot ID:
- P25311
- Entry Name:
- ZA2G_HUMAN
- Status:
- reviewed
- Protein Names:
- Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)
- Gene Names:
- AZGP1 ZAG ZNGP1
- Gene Names Primary:
- AZGP1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 298
- Sequence:
- MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids.
- Gene Ontology Go:
- extracellular exosome
extracellular region
extracellular space
MHC class I protein complex
nucleus
plasma membrane
antigen binding
glycoprotein binding
peptide antigen binding
protein transmembrane transporter activity
ribonuclease activity
antigen processing and presentation
antigen processing and presentation of peptide antigen via MHC class I
cell adhesion
detection of chemical stimulus involved in sensory perception of bitter taste
immune response
negative regulation of cell proliferation
protein transmembrane transport
retina homeostasis
RNA phosphodiester bond hydrolysis
transmembrane transport - Gene Ontology Biological Process:
- antigen processing and presentation
antigen processing and presentation of peptide antigen via MHC class I
cell adhesion
detection of chemical stimulus involved in sensory perception of bitter taste
immune response
negative regulation of cell proliferation
protein transmembrane transport
retina homeostasis
RNA phosphodiester bond hydrolysis
transmembrane transport - Gene Ontology Molecular Function:
- antigen binding
glycoprotein binding
peptide antigen binding
protein transmembrane transporter activity
ribonuclease activity - Gene Ontology Cellular Component:
- extracellular exosome
extracellular region
extracellular space
MHC class I protein complex
nucleus
plasma membrane - Keywords:
- 3D-structure
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Pyrrolidone carboxylic acid
Reference proteome
Secreted
Signal