Names & Taxonomy

Uniprot ID:
P0CG29
Entry Name:
GST2_HUMAN
Status:
reviewed
Protein Names:
Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2)
Gene Names:
GSTT2
Gene Names Primary:
GSTT2
Organism:
Homo sapiens (Human)

Structure

Length:
244
Sequence:
MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cytoplasm.

Function

Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
Catalytic Activity:
RX + glutathione = HX + R-S-glutathione.
Gene Ontology Go:
cytoplasm
extracellular exosome
glutathione transferase activity
glutathione metabolic process
Gene Ontology Biological Process:
glutathione metabolic process
Gene Ontology Molecular Function:
glutathione transferase activity
Gene Ontology Cellular Component:
cytoplasm
extracellular exosome
Keywords:
3D-structure
Complete proteome
Cytoplasm
Direct protein sequencing
Reference proteome
Transferase

Publication

PubMed ID:
10975610 10591208 1417752 8761485