Names & Taxonomy
- Uniprot ID:
- P08185
- Entry Name:
- CBG_HUMAN
- Status:
- reviewed
- Protein Names:
- Corticosteroid-binding globulin (CBG) (Serpin A6) (Transcortin)
- Gene Names:
- SERPINA6 CBG
- Gene Names Primary:
- SERPINA6
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 405
- Sequence:
- MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
- Cross Reference Drug Bank:
- DB00240 DB00394 DB01410 DB00663 DB00180 DB00591 DB01047 DB00324 DB00846 DB00588 DB00596 DB00741 DB00253 DB00648 DB01384 DB00860 DB00896 DB00620
- Gene Ontology Go:
- extracellular exosome
extracellular space
serine-type endopeptidase inhibitor activity
steroid binding
glucocorticoid metabolic process
negative regulation of endopeptidase activity
transport - Gene Ontology Biological Process:
- glucocorticoid metabolic process
negative regulation of endopeptidase activity
transport - Gene Ontology Molecular Function:
- serine-type endopeptidase inhibitor activity
steroid binding - Gene Ontology Cellular Component:
- extracellular exosome
extracellular space - Keywords:
- 3D-structure
Complete proteome
Direct protein sequencing
Disease mutation
Glycoprotein
Lipid-binding
Polymorphism
Reference proteome
Secreted
Signal
Steroid-binding
Transport