Names & Taxonomy
- Uniprot ID:
- P07098
- Entry Name:
- LIPG_HUMAN
- Status:
- reviewed
- Protein Names:
- Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3)
- Gene Names:
- LIPF
- Gene Names Primary:
- LIPF
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 398
- Sequence:
- MWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Catalytic Activity:
- Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
- Active Site:
- ACT_SITE 172 172 Nucleophile.
- Cross Reference Drug Bank:
- DB01083
- Gene Ontology Go:
- extracellular region
mitochondrion
lipid binding
malate dehydrogenase activity
triglyceride lipase activity
lipid catabolic process
malate metabolic process
triglyceride metabolic process - Gene Ontology Biological Process:
- lipid catabolic process
malate metabolic process
triglyceride metabolic process - Gene Ontology Molecular Function:
- lipid binding
malate dehydrogenase activity
triglyceride lipase activity - Gene Ontology Cellular Component:
- extracellular region
mitochondrion - Keywords:
- 3D-structure
Alternative splicing
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Hydrolase
Lipid degradation
Lipid metabolism
Polymorphism
Reference proteome
Secreted
Signal