Names & Taxonomy
- Uniprot ID:
- P05413
- Entry Name:
- FABPH_HUMAN
- Status:
- reviewed
- Protein Names:
- Fatty acid-binding protein, heart (Fatty acid-binding protein 3) (Heart-type fatty acid-binding protein) (H-FABP) (Mammary-derived growth inhibitor) (MDGI) (Muscle fatty acid-binding protein) (M-FABP)
- Gene Names:
- FABP3 FABP11 MDGI
- Gene Names Primary:
- FABP3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 133
- Sequence:
- MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm.
Function
- Function:
- FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
- Cross Reference Drug Bank:
- DB04224
- Gene Ontology Go:
- cytosol
extracellular exosome
extracellular space
sarcoplasm
cytoskeletal protein binding
icosatetraenoic acid binding
long-chain fatty acid binding
long-chain fatty acid transporter activity
oleic acid binding
cholesterol homeostasis
fatty acid metabolic process
long-chain fatty acid import
negative regulation of cell proliferation
phospholipid homeostasis
positive regulation of phospholipid biosynthetic process
regulation of fatty acid oxidation
response to drug
response to fatty acid
response to insulin
small molecule metabolic process
triglyceride catabolic process - Gene Ontology Biological Process:
- cholesterol homeostasis
fatty acid metabolic process
long-chain fatty acid import
negative regulation of cell proliferation
phospholipid homeostasis
positive regulation of phospholipid biosynthetic process
regulation of fatty acid oxidation
response to drug
response to fatty acid
response to insulin
small molecule metabolic process
triglyceride catabolic process - Gene Ontology Molecular Function:
- cytoskeletal protein binding
icosatetraenoic acid binding
long-chain fatty acid binding
long-chain fatty acid transporter activity
oleic acid binding - Gene Ontology Cellular Component:
- cytosol
extracellular exosome
extracellular space
sarcoplasm - Keywords:
- 3D-structure
Acetylation
Complete proteome
Cytoplasm
Direct protein sequencing
Lipid-binding
Phosphoprotein
Polymorphism
Reference proteome
Transport - Interacts With:
- P05556; P37198; A0MZ66