Names & Taxonomy
- Uniprot ID:
- P04118
- Entry Name:
- COL_HUMAN
- Status:
- reviewed
- Protein Names:
- Colipase
- Gene Names:
- CLPS
- Gene Names Primary:
- CLPS
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 112
- Sequence:
- MEKILILLLVALSVAYAAPGPRGIIINLENGELCMNSAQCKSNCCQHSSALGLARCTSMASENSECSVKTLYGIYYKCPCERGLTCEGDKTIVGSITNTNFGICHDAGRSKQ
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.; Enterostatin has a biological activity as a satiety signal.
- Gene Ontology Go:
- extracellular exosome
extracellular region
enzyme activator activity
fat-soluble vitamin metabolic process
lipid catabolic process
lipid digestion
lipid metabolic process
phototransduction, visible light
post-embryonic development
response to food
retinoid metabolic process
small molecule metabolic process
vitamin metabolic process - Gene Ontology Biological Process:
- fat-soluble vitamin metabolic process
lipid catabolic process
lipid digestion
lipid metabolic process
phototransduction, visible light
post-embryonic development
response to food
retinoid metabolic process
small molecule metabolic process
vitamin metabolic process - Gene Ontology Molecular Function:
- enzyme activator activity
- Gene Ontology Cellular Component:
- extracellular exosome
extracellular region - Keywords:
- Complete proteome
Diabetes mellitus
Digestion
Direct protein sequencing
Disulfide bond
Lipid degradation
Lipid metabolism
Polymorphism
Reference proteome
Secreted
Signal