Names & Taxonomy
- Uniprot ID:
- P04000
- Entry Name:
- OPSR_HUMAN
- Status:
- reviewed
- Protein Names:
- Long-wave-sensitive opsin 1 (Red cone photoreceptor pigment) (Red-sensitive opsin) (ROP)
- Gene Names:
- OPN1LW RCP
- Gene Names Primary:
- OPN1LW
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 364
- Sequence:
- MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
Function
- Function:
- Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.
- Gene Ontology Go:
- integral component of plasma membrane
photoreceptor outer segment membrane
G-protein coupled receptor activity
photoreceptor activity
phototransduction, visible light
positive regulation of cytokinesis
protein-chromophore linkage
retinoid metabolic process
signal transduction
visual perception - Gene Ontology Biological Process:
- phototransduction, visible light
positive regulation of cytokinesis
protein-chromophore linkage
retinoid metabolic process
signal transduction
visual perception - Gene Ontology Molecular Function:
- G-protein coupled receptor activity
photoreceptor activity - Gene Ontology Cellular Component:
- integral component of plasma membrane
photoreceptor outer segment membrane - Keywords:
- 3D-structure
Chromophore
Complete proteome
Disease mutation
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Phosphoprotein
Photoreceptor protein
Polymorphism
Receptor
Reference proteome
Retinal protein
Sensory transduction
Transducer
Transmembrane
Transmembrane helix
Vision