Names & Taxonomy

Uniprot ID:
P03999
Entry Name:
OPSB_HUMAN
Status:
reviewed
Protein Names:
Short-wave-sensitive opsin 1 (Blue cone photoreceptor pigment) (Blue-sensitive opsin) (BOP)
Gene Names:
OPN1SW BCP
Gene Names Primary:
OPN1SW
Organism:
Homo sapiens (Human)

Structure

Length:
348
Sequence:
MRKMSEEEFYLFKNISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQVGPN
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane; Multi-pass membrane protein.

Function

Function:
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.
Gene Ontology Go:
integral component of plasma membrane
photoreceptor outer segment membrane
G-protein coupled receptor activity
photoreceptor activity
receptor activity
phototransduction
phototransduction, visible light
protein-chromophore linkage
retinoid metabolic process
signal transduction
visual perception
Gene Ontology Biological Process:
phototransduction
phototransduction, visible light
protein-chromophore linkage
retinoid metabolic process
signal transduction
visual perception
Gene Ontology Molecular Function:
G-protein coupled receptor activity
photoreceptor activity
receptor activity
Gene Ontology Cellular Component:
integral component of plasma membrane
photoreceptor outer segment membrane
Keywords:
3D-structure
Chromophore
Complete proteome
Disease mutation
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Phosphoprotein
Photoreceptor protein
Receptor
Reference proteome
Retinal protein
Sensory transduction
Transducer
Transmembrane
Transmembrane helix
Vision

Publication

PubMed ID:
2937147 9089077 2565599 3303660 1531728 1386496