Names & Taxonomy

Uniprot ID:
P01834
Entry Name:
IGKC_HUMAN
Status:
reviewed
Protein Names:
Ig kappa chain C region
Gene Names:
IGKC
Gene Names Primary:
IGKC
Organism:
Homo sapiens (Human)

Structure

Length:
106
Sequence:
TVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Proteomes:
UP000005640

Function

Gene Ontology Go:
blood microparticle
external side of plasma membrane
extracellular exosome
extracellular region
extracellular space
immunoglobulin complex, circulating
plasma membrane
antigen binding
immunoglobulin receptor binding
B cell receptor signaling pathway
complement activation
complement activation, classical pathway
defense response to bacterium
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
immune response
innate immune response
phagocytosis, engulfment
phagocytosis, recognition
positive regulation of B cell activation
receptor-mediated endocytosis
regulation of immune response
retina homeostasis
Gene Ontology Biological Process:
B cell receptor signaling pathway
complement activation
complement activation, classical pathway
defense response to bacterium
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
immune response
innate immune response
phagocytosis, engulfment
phagocytosis, recognition
positive regulation of B cell activation
receptor-mediated endocytosis
regulation of immune response
retina homeostasis
Gene Ontology Molecular Function:
antigen binding
immunoglobulin receptor binding
Gene Ontology Cellular Component:
blood microparticle
external side of plasma membrane
extracellular exosome
extracellular region
extracellular space
immunoglobulin complex, circulating
plasma membrane
Keywords:
3D-structure
Complete proteome
Direct protein sequencing
Disease mutation
Disulfide bond
Immunoglobulin C region
Immunoglobulin domain
Reference proteome

Publication

PubMed ID:
5489770 4923144 5027703 6775818 5586923 4893682 5447531 9588180 25946035 3931219