Names & Taxonomy
- Uniprot ID:
- P00709
- Entry Name:
- LALBA_HUMAN
- Status:
- reviewed
- Protein Names:
- Alpha-lactalbumin (Lactose synthase B protein) (Lysozyme-like protein 7)
- Gene Names:
- LALBA LYZL7
- Gene Names Primary:
- LALBA
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 142
- Sequence:
- MRFFVPLFLVGILFPAILAKQFTKCELSQLLKDIDGYGGIALPELICTMFHTSGYDTQAIVENNESTEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKILDIKGIDYWLAHKALCTEKLEQWLCEKL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
- Gene Ontology Go:
- extracellular space
Golgi lumen
Golgi membrane
calcium ion binding
lactose synthase activity
apoptotic process
carbohydrate metabolic process
cell-cell signaling
defense response to bacterium
lactose biosynthetic process
signal transduction
small molecule metabolic process - Gene Ontology Biological Process:
- apoptotic process
carbohydrate metabolic process
cell-cell signaling
defense response to bacterium
lactose biosynthetic process
signal transduction
small molecule metabolic process - Gene Ontology Molecular Function:
- calcium ion binding
lactose synthase activity - Gene Ontology Cellular Component:
- extracellular space
Golgi lumen
Golgi membrane - Keywords:
- 3D-structure
Calcium
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Lactose biosynthesis
Metal-binding
Milk protein
Polymorphism
Reference proteome
Secreted
Signal