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Uniprot ID:: O95302
Entry Name:: FKBP9_HUMAN
Status:: reviewed
Protein Names:: Peptidyl-prolyl cis-trans isomerase FKBP9 (PPIase FKBP9) (EC 5.2.1.8) (63 kDa FK506-binding protein) (63 kDa FKBP) (FKBP-63) (FK506-binding protein 9) (FKBP-9) (Rotamase)
Gene Names:: FKBP9 FKBP60 FKBP63
Gene Names Primary:: FKBP9
Organism:: Homo sapiens (Human)

Length:: 570
Sequence:: MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPEGYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFDAELIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL
Proteomes:: UP000005640

Function:: PPIases accelerate the folding of proteins during protein synthesis.
Catalytic Activity:: Peptidylproline (omega=180) = peptidylproline (omega=0).
Enzyme Regulation:: ENZYME REGULATION: Inhibited by FK506.
Gene Ontology Go:: endoplasmic reticulum
endoplasmic reticulum membrane
calcium ion binding
FK506 binding
peptidyl-prolyl cis-trans isomerase activity
chaperone-mediated protein folding
protein folding
protein peptidyl-prolyl isomerization
Gene Ontology Biological Process:: chaperone-mediated protein folding
protein folding
protein peptidyl-prolyl isomerization
Gene Ontology Molecular Function:: calcium ion binding
FK506 binding
peptidyl-prolyl cis-trans isomerase activity
Gene Ontology Cellular Component:: endoplasmic reticulum
endoplasmic reticulum membrane
Keywords:: Alternative splicing
Calcium
Complete proteome
Endoplasmic reticulum
Glycoprotein
Isomerase
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Rotamase
Signal