Names & Taxonomy
- Uniprot ID:
- O60664
- Entry Name:
- PLIN3_HUMAN
- Status:
- reviewed
- Protein Names:
- Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17)
- Gene Names:
- PLIN3 M6PRBP1 TIP47
- Gene Names Primary:
- PLIN3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 434
- Sequence:
- MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEKAPEEKK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
- Cross Reference Drug Bank:
- DB01279 DB01271
- Gene Ontology Go:
- cytoplasm
endosome
endosome membrane
Golgi apparatus
intracellular membrane-bounded organelle
lipid particle
membrane
vesicle-mediated transport - Gene Ontology Biological Process:
- vesicle-mediated transport
- Gene Ontology Cellular Component:
- cytoplasm
endosome
endosome membrane
Golgi apparatus
intracellular membrane-bounded organelle
lipid particle
membrane - Keywords:
- Acetylation
Alternative splicing
Coiled coil
Complete proteome
Cytoplasm
Endosome
Lipid droplet
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Transport - Interacts With:
- Q9WMX2; Q96DZ9