Names & Taxonomy
- Uniprot ID:
- O60647
- Entry Name:
- O60647_HUMAN
- Status:
- unreviewed
- Protein Names:
- Eyes absent homolog (EC 3.1.3.48) (Fragment)
- Gene Names:
- Eab1
- Gene Names Primary:
- Eab1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 434
- Sequence:
- DSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Function
- Catalytic Activity:
- Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
- Cofactor:
- COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Gene Ontology Go:
- metal ion binding
protein tyrosine phosphatase activity
multicellular organism development
regulation of transcription, DNA-templated
striated muscle tissue development - Gene Ontology Biological Process:
- multicellular organism development
regulation of transcription, DNA-templated
striated muscle tissue development - Gene Ontology Molecular Function:
- metal ion binding
protein tyrosine phosphatase activity - Keywords:
- Hydrolase
Magnesium
Metal-binding
Protein phosphatase
Transcription
Transcription regulation