Names & Taxonomy

Uniprot ID:
O14520
Entry Name:
AQP7_HUMAN
Status:
reviewed
Protein Names:
Aquaporin-7 (AQP-7) (Aquaglyceroporin-7) (Aquaporin adipose) (AQPap) (Aquaporin-7-like)
Gene Names:
AQP7 AQP7L AQP9
Gene Names Primary:
AQP7
Organism:
Homo sapiens (Human)

Structure

Length:
342
Sequence:
MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane; Multi-pass membrane protein.

Function

Function:
Forms a channel for water and glycerol.
Gene Ontology Go:
cell-cell junction
cytoplasm
integral component of plasma membrane
plasma membrane
glycerol channel activity
urea transmembrane transporter activity
water channel activity
excretion
generation of precursor metabolites and energy
glycerol transport
ion transmembrane transport
transmembrane transport
urea transmembrane transport
water transport
Gene Ontology Biological Process:
excretion
generation of precursor metabolites and energy
glycerol transport
ion transmembrane transport
transmembrane transport
urea transmembrane transport
water transport
Gene Ontology Molecular Function:
glycerol channel activity
urea transmembrane transporter activity
water channel activity
Gene Ontology Cellular Component:
cell-cell junction
cytoplasm
integral component of plasma membrane
plasma membrane
Keywords:
Alternative splicing
Complete proteome
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Repeat
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
9405233 11952783 14702039 15164053 15489334 17566090