Names & Taxonomy
- Uniprot ID:
- O00244
- Entry Name:
- ATOX1_HUMAN
- Status:
- reviewed
- Protein Names:
- Copper transport protein ATOX1 (Metal transport protein ATX1)
- Gene Names:
- ATOX1 HAH1
- Gene Names Primary:
- ATOX1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 68
- Sequence:
- MPKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTLLATLKKTGKTVSYLGLE
- Proteomes:
- UP000005640
Function
- Function:
- Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.
- Gene Ontology Go:
- cytosol
copper chaperone activity
copper ion binding
copper ion transmembrane transporter activity
copper-dependent protein binding
metallochaperone activity
cellular copper ion homeostasis
copper ion transport
intracellular copper ion transport
response to oxidative stress
response to reactive oxygen species - Gene Ontology Biological Process:
- cellular copper ion homeostasis
copper ion transport
intracellular copper ion transport
response to oxidative stress
response to reactive oxygen species - Gene Ontology Molecular Function:
- copper chaperone activity
copper-dependent protein binding
copper ion binding
copper ion transmembrane transporter activity
metallochaperone activity - Gene Ontology Cellular Component:
- cytosol
- Keywords:
- 3D-structure
Acetylation
Chaperone
Complete proteome
Copper
Copper transport
Ion transport
Metal-binding
Reference proteome
Transport - Interacts With:
- O43822; Q9NWS6; O95749