Names & Taxonomy

Uniprot ID:
L7RXH0
Entry Name:
L7RXH0_HUMAN
Status:
unreviewed
Protein Names:
Integrin, alpha V
Gene Names:
ITGAV
Gene Names Primary:
ITGAV
Organism:
Homo sapiens (Human)

Structure

Length:
1048
Sequence:
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Subcellular location

Subcellular Location:
Membrane

Function

Gene Ontology Go:
external side of plasma membrane
integrin complex
intracellular
apoptotic cell clearance
blood vessel development
cell adhesion
ERK1 and ERK2 cascade
extrinsic apoptotic signaling pathway in absence of ligand
integrin-mediated signaling pathway
positive regulation of cell migration
positive regulation of osteoblast proliferation
regulation of apoptotic cell clearance
Gene Ontology Biological Process:
apoptotic cell clearance
blood vessel development
cell adhesion
ERK1 and ERK2 cascade
extrinsic apoptotic signaling pathway in absence of ligand
integrin-mediated signaling pathway
positive regulation of cell migration
positive regulation of osteoblast proliferation
regulation of apoptotic cell clearance
Gene Ontology Cellular Component:
external side of plasma membrane
integrin complex
intracellular
Keywords:
Cell adhesion
Integrin
Membrane
Receptor
Repeat
Signal
Transmembrane
Transmembrane helix