Names & Taxonomy
- Uniprot ID:
- J3KQE5
- Entry Name:
- J3KQE5_HUMAN
- Status:
- unreviewed
- Protein Names:
- GTP-binding nuclear protein Ran (Fragment)
- Gene Names:
- RAN
- Gene Names Primary:
- RAN
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 234
- Sequence:
- RRRRLRLRRLNCASAIFPASVGRARRRFWKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Nucleus
Function
- Function:
- GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
- Gene Ontology Go:
- intracellular
GTP binding
GTPase activity
intracellular protein transport
nucleocytoplasmic transport
small GTPase mediated signal transduction - Gene Ontology Biological Process:
- intracellular protein transport
nucleocytoplasmic transport
small GTPase mediated signal transduction - Gene Ontology Molecular Function:
- GTPase activity
GTP binding - Gene Ontology Cellular Component:
- intracellular
- Keywords:
- Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Protein transport
Proteomics identification
Reference proteome
Transport