Names & Taxonomy

Uniprot ID:
J3KQE5
Entry Name:
J3KQE5_HUMAN
Status:
unreviewed
Protein Names:
GTP-binding nuclear protein Ran (Fragment)
Gene Names:
RAN
Gene Names Primary:
RAN
Organism:
Homo sapiens (Human)

Structure

Length:
234
Sequence:
RRRRLRLRRLNCASAIFPASVGRARRRFWKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Nucleus

Function

Function:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
Gene Ontology Go:
intracellular
GTP binding
GTPase activity
intracellular protein transport
nucleocytoplasmic transport
small GTPase mediated signal transduction
Gene Ontology Biological Process:
intracellular protein transport
nucleocytoplasmic transport
small GTPase mediated signal transduction
Gene Ontology Molecular Function:
GTPase activity
GTP binding
Gene Ontology Cellular Component:
intracellular
Keywords:
Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Protein transport
Proteomics identification
Reference proteome
Transport

Publication

PubMed ID:
16541075 19608861 21269460 24275569 25944712