Names & Taxonomy

Uniprot ID:
A0A067XG54
Entry Name:
A0A067XG54_HUMAN
Status:
unreviewed
Protein Names:
Phospholipid-transporting ATPase (EC 3.6.3.1)
Gene Names:
ATP11C
Gene Names Primary:
ATP11C
Organism:
Homo sapiens (Human)

Structure

Length:
1113
Sequence:
MFRRSLNRFCAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDCLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLKNVRRRSARNPNLELPMLLSYKHTDSGYS
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane

Function

Catalytic Activity:
ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).
Gene Ontology Go:
integral component of membrane
ATP binding
magnesium ion binding
phospholipid-translocating ATPase activity
Gene Ontology Molecular Function:
ATP binding
magnesium ion binding
phospholipid-translocating ATPase activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
ATP-binding
Coiled coil
Complete proteome
Hydrolase
Magnesium
Membrane
Nucleotide-binding
Proteomics identification
Reference proteome
Transmembrane
Transmembrane helix

Publication

PubMed ID:
15772651 17525332 18669648 19413330 19690332 21406692 24275569