Names & Taxonomy

Uniprot ID:
E9PCM2
Entry Name:
E9PCM2_HUMAN
Status:
unreviewed
Protein Names:
Prestin (Solute carrier family 26 member 5)
Gene Names:
SLC26A5
Gene Names Primary:
SLC26A5
Organism:
Homo sapiens (Human)

Structure

Length:
707
Sequence:
MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALAEQEASAPPSQEDLEPNATPATPEA
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane

Function

Function:
Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ.
Gene Ontology Go:
integral component of membrane
secondary active sulfate transmembrane transporter activity
regulation of cell shape
sensory perception of sound
Gene Ontology Biological Process:
regulation of cell shape
sensory perception of sound
Gene Ontology Molecular Function:
secondary active sulfate transmembrane transporter activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
Cell shape
Complete proteome
Hearing
Membrane
Motor protein
Reference proteome
Transmembrane
Transmembrane helix

Publication

PubMed ID:
12853948