Names & Taxonomy

Uniprot ID:
A0A024R6R4
Entry Name:
A0A024R6R4_HUMAN
Status:
unreviewed
Protein Names:
Matrix metallopeptidase 2 (Gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), isoform CRA_a
Gene Names:
MMP2 hCG_24148
Gene Names Orf:
hCG_24148
Gene Names Primary:
MMP2
Organism:
Homo sapiens (Human)

Structure

Length:
660
Sequence:
MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC

Function

Gene Ontology Go:
extracellular matrix
extracellular space
mitochondrion
plasma membrane
sarcomere
metalloendopeptidase activity
zinc ion binding
blood vessel maturation
bone trabecula formation
cellular response to amino acid stimulus
collagen catabolic process
embryo implantation
face morphogenesis
intramembranous ossification
positive regulation of innate immune response
response to hypoxia
Gene Ontology Biological Process:
blood vessel maturation
bone trabecula formation
cellular response to amino acid stimulus
collagen catabolic process
embryo implantation
face morphogenesis
intramembranous ossification
positive regulation of innate immune response
response to hypoxia
Gene Ontology Molecular Function:
metalloendopeptidase activity
zinc ion binding
Gene Ontology Cellular Component:
extracellular matrix
extracellular space
mitochondrion
plasma membrane
sarcomere
Keywords:
Calcium
Disulfide bond
Hydrolase
Metal-binding
Metalloprotease
Protease
Repeat
Signal
Zinc

Publication

PubMed ID:
11181995